TY - T1 - Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study SN - / UR - http://hdl.handle.net/10138/183446 T3 - A1 - de Mello, Vanessa D.; Paananen, Jussi; Lindstrom, Jaana; Lankinen, Maria A.; Shi, Lin; Kuusisto, Johanna; Pihlajamaki, Jussi; Auriola, Seppo; Lehtonen, Marko; Rolandsson, Olov; Bergdahl, Ingvar A.; Nordin, Elise; Ilanne-Parikka, Pirjo; Keinanen-Kiukaanniemi, Sirkka; Landberg, Rikard; Eriksson, Johan G.; Tuomilehto, Jaakko; Hanhineva, Kati; Uusitupa, Matti A2 - PB - Y1 - 2017 LA - eng AB - Wide-scale profiling technologies including metabolomics broaden the possibility of novel discoveries related to the pathogenesis of type 2 diabetes (T2D). By applying non-targeted metabolomics approach, we investigated here whether serum metabolite profile predicts T2D in a well-characterized study population with impaired glucose tolerance by examining two groups of individuals who took part in the Finnish Diabetes Prevention Study (DPS); those who either early developed T2D (n = 96) or did no... VO - IS - SP - OP - KW - IMPAIRED GLUCOSE-TOLERANCE; INSULIN SENSITIVITY; INDOLE-3-PROPIONIC ACID; MASS-SPECTROMETRY; INDOLIC COMPOUNDS; GUT MICROBIOTA; AMINO-ACIDS; FATTY-ACIDS; LIFE-STYLE; BIOMARKERS; 3111 Biomedicine N1 - PP - ER -