TY  -  
T1  - Influenza A Virus Infection Induces Hyperresponsiveness in Human Lung Tissue-Resident and Peripheral Blood NK Cells 
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UR  - http://hdl.handle.net/10138/303522 
T3  -  
A1  - Scharenberg, Marlena; Vangeti, Sindhu; Kekäläinen, Eliisa; Bergman, Per; Al-Ameri, Mamdoh; Johansson, Niclas; Sonden, Klara; Falck-Jones, Sara; Färnert, Anna; Ljunggren, Hans-Gustaf; Michaelsson, Jakob; Smed-Sörensen, Anna; Marquardt, Nicole 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - NK cells in the human lung respond to influenza A virus-(IAV-) infected target cells. However, the detailed functional capacity of human lung and peripheral blood NK cells remains to be determined in IAV and other respiratory viral infections. Here, we investigated the effects of IAV infection on human lung and peripheral blood NK cells in vitro and ex vivo following clinical infection. IAV infection of lung- and peripheral blood-derived mononuclear cells in vitro induced NK cell hyperresponsive... 
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KW  - human; lung; NK cells; influenza A virus; viral pathogenesis; respiratory infections; NATURAL-KILLER-CELLS; IMMUNE INJURY; EXPRESSION; IP-10; ACTIVATION; IL-15; CXCR3; H5N1; 3111 Biomedicine; 3121 General medicine, internal medicine and other clinical medicine 
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