TY  -  
T1  - Investigating the differential expression of sirtuins and microRNA in cardiac tissue of neonatal mice 
SN  -  /  
UR  - URN:NBN:fi:hulib-201705104089; http://hdl.handle.net/10138/184223 
T3  -  
A1  - Yoo, Bo Ram 
A2  -  
PB  - Helsingfors universitet 
Y1  - 2017 
LA  - eng 
AB  - Cardiovascular disease is one of the leading causes of mortality worldwide. Upon myocardial infarction, billions of cardiomyocytes are lost, a fibrotic scar forms, and the heart's contractile function is compromised. Mammalian cardiomyocytes lose most of their proliferative capacity shortly after birth. This decline in proliferative capacity is associated with a switch from glycolysis to oxidative phosphorylation, yielding more ATP, but also inevitably forming reactive oxygen species (ROS). Ther... 
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KW  - regenerative; pharmacology; cardiac regeneration; Sirtuins; microRNA; protein; gene; expression; Pharmacology; Farmakologia; Farmakologi 
N1  -   
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ER  -