TY - T1 - Is Brain-Derived Neurotrophic Factor Associated With Smoking Initiation? Replication Using a Large Finnish Population Sample : Replication Using a Large Finnish Population Sample SN - / UR - http://hdl.handle.net/10138/321651 T3 - A1 - Korhonen, Tellervo; Loukola, Anu; Hällfors, Jenni; Salomaa, Minna-Maija; Salomaa, Veikko; Kaprio, Jaakko A2 - PB - Y1 - 2020 LA - eng AB - Introduction: Brain-derived neurotrophic factor (BDNF) is a growth factor in the central nervous system. There is evidence for the involvement of BDNF in addictions and mental disorders. We aimed to replicate the earlier reported association of a functional genetic variant of BDNF with smoking initiation (SI) using a large population-based sample and to test whether the association is independent of depression. Methods: Our sample was drawn from the Finnish population-based FINRISK surveys condu... VO - IS - SP - OP - KW - 3142 Public health care science, environmental and occupational health; FACTOR BDNF; DEPRESSION; BEHAVIOR N1 - PP - ER -