TY  -  
T1  - Isolation, characterization and antifungal docking studies of wortmannin isolated from Penicillium radicum 
SN  -  /  
UR  - http://hdl.handle.net/10138/162438 
T3  -  
A1  - Singh, Vineeta; Praveen, Vandana; Tripathi, Divya; Haque, Shafiul; Somvanshi, Pallavi; Katti, S. B.; Tripathi, C. K. M. 
A2  -  
PB  -  
Y1  - 2015 
LA  - eng 
AB  - During the search for a potent antifungal drug, a cell-permeable metabolite was isolated from a soil isolate taxonomically identified as Penicillium radicum. The strain was found to be a potent antifungal agent. Production conditions of the active compound were optimized and the active compound was isolated, purified, characterized and identified as a phosphoinositide 3-kinase (PI3K) inhibitor, commonly known as wortmannin (Wtmn). This is very first time we are reporting the production of Wtmn f... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - AEROMONAS-HYDROPHILA; NEGATIVE REGULATION; INHIBITOR; 3-KINASE; BIOSYNTHESIS; PURIFICATION; EFFICIENT; WHEAT; 317 Pharmacy 
N1  -   
PP  -  
ER  -