TY - T1 - Ketoprofeenin biologinen käytettävyys ja farmakokinetiikka sioilla eri antotavoilla ja ketoprofeeniyliannoksen farmakokinetiikka ja vaikutus munuaisiin lampailla SN - / UR - URN:NBN:fi-fe201801151143; http://hdl.handle.net/10138/27426 T3 - A1 - Keltto, Katri A2 - PB - Helsingfors universitet Y1 - 2011 LA - fin AB - Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) widely used for the treatment of pain in sheep and swine. Information of correct ketoprofen doses in different animal species is limited. The correct dose cannot be reliably extrapolated based on other species or human. The problem in cases of suspected overdose is knowing whether the given dose was toxic. The objective of the study with sheep was to figure out if the kinetics of ketoprofen is altered by a tenfold overdose, study the e... VO - IS - SP - OP - KW - ketoprofen; bioavailability; pharmacokinetics; overdose; kidney; swine; pig; sheep; ketoprofeeni; biologinen käytettävyys; farmakokinetiikka; yliannos; munuainen; sika; lammas; Biofarmaci; Biopharmacy; Biofarmasia N1 - PP - ER -