TY  -  
T1  - Label-free tissue proteomics can classify oral squamous cell carcinoma from healthy tissue in a stage-specific manner 
SN  -  /  
UR  - http://hdl.handle.net/10138/265533 
T3  -  
A1  - Dickinson, Amy; Saraswat, Mayank; Mäkitie, Antti; Silen, Robert; Hagström, Jaana; Haglund, Caj; Joenväärä, Sakari; Silen, Suvi 
A2  -  
PB  -  
Y1  - 2018 
LA  - eng 
AB  - Objectives: No prognostic or predictive biomarkers for oral squamous cell carcinoma (OSCC) exist. We aimed to discover novel proteins, altered in OSCC, to be further investigated as potential biomarkers, and to improve understanding about pathways involved in OSCC. Materials and Methods: Proteomic signatures of seven paired healthy and OSCC tissue samples were identified using ultra-definition quantitative mass spectrometry, then analysed and compared using Anova, principal component analysis, h... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - Oral squamous cell carcinoma; Head and neck cancer; Tongue cancer; OPLS-DA; Tissue proteomics; CA1; S100A7; Neutrophil defensin 1; ANP32B; Immunohistochemistry; SIGNALING PATHWAY; CANCER; OVEREXPRESSION; EXPRESSION; IDENTIFICATION; TUMORIGENESIS; BIOMARKERS; THERAPY; MARKERS; TONGUE; 3122 Cancers; 313 Dentistry; 3126 Surgery, anesthesiology, intensive care, radiology 
N1  -   
PP  -  
ER  -