TY - T1 - Latent TGF-β binding proteins -3 and -4 : transcriptional control and extracellular matrix targeting SN - / UR - URN:ISBN:978-952-10-6418-0; http://hdl.handle.net/10138/20492 T3 - A1 - Kantola, Anna A2 - PB - Helsingin yliopisto Y1 - 2010 LA - en AB - Extracellular matrix (ECM) is a complex network of various proteins and proteoglycans which provides tissues with structural strength and resilience. By harvesting signaling molecules like growth factors ECM has the capacity to control cellular functions including proliferation, differentiation and cell survival. Latent transforming growth factor β (TGF-β) binding proteins (LTBPs) associate fibrillar structures of the ECM and mediate the efficient secretion and ECM deposition of latent TGF-β. Th... VO - IS - SP - OP - KW - solubiologia N1 - PP - ER -