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T1  - Levels of glial cell line-derived neurotrophic factor are decreased, but fibroblast growth factor 2 and cerebral dopamine neurotrophic factor are increased in the hippocampus in parkinson's disease 
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UR  - http://hdl.handle.net/10138/314480 
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A1  - Virachit, Sophie; Mathews, Kathryn J.; Cottam, Veronica; Werry, Eryn; Galli, Emilia; Rappou, Elisabeth; Lindholm, Pӓivi; Saarma, Mart; Halliday, Glenda M.; Weickert, Cynthia Shannon; Double, Kay L. 
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Y1  - 2019 
LA  - eng 
AB  - Growth factors can facilitate hippocampus-based learning and memory and are potential targets for treatment of cognitive dysfunction via their neuroprotective and neurorestorative effects. Dementia is common in Parkinson's disease (PD), but treatment options are limited. We aimed to determine if levels of growth factors are altered in the hippocampus of patients with PD, and if such alterations are associated with PD pathology. Enzyme-linked immunosorbent assays were used to quantify seven growt... 
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KW  - 3112 Neurosciences; Parkinson's disease; hippocampus; fibroblast growth factor 2; glial cell line-derived neurotrophic factor; cerebral dopamine neurotrophic factor; ALZHEIMERS-DISEASE; CDNF/MANF FAMILY; ENDOPLASMIC-RETICULUM STRESS; ALPHA-SYNUCLEIN; MILD COGNITIVE IMPAIRMENT; SUBSTANTIA-NIGRA; RAT MODEL; LOCUS-COERULEUS; LONG-TERM POTENTIATION; QUALITY-OF-LIFE; 3124 Neurology and psychiatry; 3111 Biomedicine 
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