TY  -  
T1  - Levosimendan in Acute and Advanced Heart Failure : an Expert Perspective on Posology and Therapeutic Application 
SN  -  /  
UR  - http://hdl.handle.net/10138/278324 
T3  -  
A1  - Bouchez, S.; Fedele, F.; Giannakoulas, G.; Gustafsson, F.; Harjola, V. -P.; Karason, K.; Kivikko, M.; von Lewinski, D.; Oliva, F.; Papp, Z.; Parissis, J.; Pollesello, Piero; Pölzl, G.; Tschöpe, C. 
A2  -  
PB  -  
Y1  - 2018 
LA  - eng 
AB  - Levosimendan, a calcium sensitizer and potassium channel-opener, is widely appreciated by many specialist heart failure practitioners for its effects on systemic and pulmonary hemodynamics and for the relief of symptoms of acute heart failure. The drug's impact on mortality in large randomized controlled trials has been inconsistent or inconclusive but, in contrast to conventional inotropes, there have been no indications of worsened survival and some signals of improved heart failure-related qu... 
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KW  - Inodilators; Inotropes; Acute heart failure; Advanced heart failure; Levosimendan; Renal function; GLOMERULAR-FILTRATION-RATE; CRITICALLY-ILL PATIENTS; CARDIAC-SURGERY; CALCIUM SENSITIZER; PERIOPERATIVE LEVOSIMENDAN; MYOCARDIAL EFFICIENCY; REPETITIVE USE; BLOOD-FLOW; METAANALYSIS; DOBUTAMINE; 3121 General medicine, internal medicine and other clinical medicine; 317 Pharmacy 
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