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T1  - Light-Activatable Assembled Nanoparticles to Improve Tumor-Penetration and Eradicate Metastasis in Triple Negative Breast Cancer 
SN  -  /  
UR  - http://hdl.handle.net/10138/327320 
T3  -  
A1  - Ji, Jianfeng; Ma, Fei; Zhang, Hongbo; Liu, Fengyong; He, Jian; Li, Wanlin; Xie,  Tingting; Zhong,  Danni; Zhang,  Tingting; Tian, Mei; Zhang, Hong; Almeida Santos, Helder; Zhou, Min 
A2  -  
PB  -  
Y1  - 2018 
LA  - eng 
AB  - Triple‐negative breast cancer (TNBC) is a kind of aggressive malignancy with fast metastatic behavior. Herein, a nanosystem loaded with a near‐infrared (NIR) agent is developed to achieve chemo‐photothermal combination therapy for inhibiting tumor growth and metastasis in TNBC. The NIR agent of ultrasmall sized copper sulfide nanodots with strong NIR light‐absorbing capability is entrapped into the doxorubicin‐contained temperature‐sensitive polymer‐based nanosystem by a self‐assembled method. T... 
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KW  - 3122 Cancers; 221 Nano-technology; 317 Pharmacy; metastasis; nanoparticles; self-assembly; triple-negative breast cancer; tumor penetration; DRUG-DELIVERY; THERAPEUTIC-EFFICACY; PHOTOTHERMAL THERAPY; RENAL CLEARANCE; MOLECULAR-BASIS; STEM-CELLS; DOXORUBICIN; SIZE; RESISTANCE; DISEASE 
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