TY  -  
T1  - Liprin-α1 modulates cancer cell signaling by transmembrane protein CD82 in adhesive membrane domains linked to cytoskeleton 
SN  -  /  
UR  - http://hdl.handle.net/10138/237148 
T3  -  
A1  - Pehkonen, Henna; Lento, Mira; von Nandelstadh, Pernilla; Filippou, Artemis; Grénman, Reidar; Lehti, Kaisa; Monni, Outi 
A2  -  
PB  - BioMed Central 
Y1  - 2018 
LA  -  
AB  - Abstract
              
                Background
                PPFIA1 is located at the 11q13 region commonly amplified in cancer. The protein liprin-α1 encoded by PPF1A1 contributes to the adhesive and invasive structures of cytoskeletal elements and is located at the invadosomes in cancer cells. However, the precise mechanism of liprin-α1 function in cancer progression has remained elusive.
              
              
                Methods
                Invasion regulating activity o... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - Liprin-α1; PPFIA1; CD82; Head and neck cancer; Breast cancer; Invasion; RNA sequencing; Three-dimensional cell culture 
N1  -   
PP  -  
ER  -