TY - T1 - Longitudinal assessment of the CXCL10 blood and urine concentration in kidney transplant recipients with BK polyomavirus replication—a retrospective study SN - / UR - http://hdl.handle.net/10138/318542 T3 - A1 - Weseslindtner, Lukas; Hedman, Lea; Wang, Yilin; Strassl, Robert; Helanterä, Ilkka; Aberle, Stephan W.; Bond, Gregor; Hedman, Klaus A2 - PB - Y1 - 2020 LA - eng AB - In kidney transplant recipients (KTRs), BK polyomavirus (BKPyV) replication may progress to polyomavirus-associated nephropathy (PVAN). In this retrospective study, we assessed the chemokine CXCL10 in urine and blood samples consecutively acquired from 85 KTRs who displayed different stages of BKPyV replication and eventually developed PVAN. In parallel to progression toward PVAN, CXCL10 gradually increased in blood and urine, from baseline (prior to virus replication) to BKPyV DNAuria (median i... VO - IS - SP - OP - KW - 3126 Surgery, anesthesiology, intensive care, radiology; BK virus; CXCL10; kidney transplantation; nephropathy; polyomavirus; RENAL-ALLOGRAFT RECIPIENTS; HUMAN CYTOMEGALOVIRUS REPLICATION; VIRUS NEPHROPATHY; IP-10; NONINVASIVE DIAGNOSIS; INFLAMMATION; REJECTION; DISEASE; CHEMOKINE; INFECTION N1 - PP - ER -