TY  -  
T1  - Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor Prognosis 
SN  -  /  
UR  - http://hdl.handle.net/10138/160529 
T3  -  
A1  - Bufalino, Andreia; Cervigne, Nilva K.; de Oliveira, Carine Ervolino; Fonseca, Felipe Paiva; Rodrigues, Priscila Campioni; Soares Macedo, Carolina Carneiro; Sobral, Lays Martin; Miguel, Marcia Costa; Lopes, Marcio Ajudarte; Paes Leme, Adriana Franco; Lambert, Daniel W.; Salo, Tuula A.; Kowalski, Luiz Paulo; Graner, Edgard; Coletta, Ricardo D. 
A2  -  
PB  -  
Y1  - 2015 
LA  - eng 
AB  - Deregulated expression of activin A is reported in several tumors, but its biological functions in oral squamous cell carcinoma (OSCC) are unknown. Here, we investigate whether activin A can play a causal role in OSCCs. Activin A expression was assessed by qPCR and immunohistochemistry in OSCC tissues. Low activin A-expressing cells were treated with recombinant activin A and assessed for apoptosis, proliferation, adhesion, migration, invasion and epithelial-mesenchymal transition (EMT). Those p... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - PROSTATE-CANCER PROGRESSION; HUMAN BREAST; TGF-BETA; MESENCHYMAL TRANSITION; PROLIFERATION; EXPRESSION; GROWTH; METASTASIS; APOPTOSIS; INVASION; 313 Dentistry; 3111 Biomedicine 
N1  -   
PP  -  
ER  -