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T1  - Lowering Low-Density Lipoprotein Cholesterol Concentration with Plant Stanol Esters to Reduce the Risk of Atherosclerotic Cardiovascular Disease Events at a Population Level : A Critical Discussion 
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UR  - http://hdl.handle.net/10138/321013 
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A1  - Gylling, Helena; Strandberg, Timo E.; Kovanen, Petri T.; Simonen, Piia 
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Y1  - 2020 
LA  - eng 
AB  - Atherosclerotic cardiovascular diseases (ASCVDs) cause every fifth death worldwide. However, it is possible to prevent the progression of ASCVDs by reducing circulating concentrations of low-density lipoprotein cholesterol (LDL-C). Recent large meta-analyses demonstrated that by reducing the dietary intake of saturated fat and cholesterol, it is possible to reduce the risk of ASCVD events. Plant stanols, as fatty-acid esters, were developed as a dietary adjunct to reduce LDL-C levels as part of ... 
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KW  - atherosclerosis; cardiovascular disease; cholesterol; lipoprotein; nutrition; plant stanol; risk reduction; DIETARY-CHOLESTEROL; SERUM-CHOLESTEROL; LDL-CHOLESTEROL; 000 PARTICIPANTS; STATIN THERAPY; ABSORPTION; METAANALYSIS; METABOLISM; EZETIMIBE; EFFICACY; 3143 Nutrition; 3121 General medicine, internal medicine and other clinical medicine 
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