TY - T1 - MMP-7 expression may influence the rate of distant recurrences and disease-specific survival in HPV-positive oropharyngeal squamous cell carcinoma SN - / UR - http://hdl.handle.net/10138/303661 T3 - A1 - Vento, Seija I.; Jouhi, Lauri; Mohamed, Hesham; Haglund, Caj; Mäkitie, Antti A.; Atula, Timo; Hagström, Jaana; Mäkinen, Laura K. A2 - PB - Y1 - 2018 LA - eng AB - The objective of this study was to determine if matrix metalloproteinase-7 (MMP-7) expression is related to human papilloma virus (HPV) status, clinical parameters, and outcome in oropharyngeal squamous cell carcinoma (OPSCC). Tumor tissue specimens from 201 OPSCC patients treated with curative intent were available for immunohistochemistry, and the samples were stained with monoclonal MMP-7 antibody. All the patients were followed up at least 3 years or until death. MMP-7 expression did not dif... VO - IS - SP - OP - KW - Oropharyngeal cancer; Matrix metalloproteinase-7; MMP-7; HPV; Survival analysis; SQUAMOCOLUMNAR JUNCTION CELLS; HUMAN-PAPILLOMAVIRUS HPV; MATRIX METALLOPROTEINASES; TISSUE INHIBITORS; UNITED-STATES; NECK CANCERS; HEAD; POPULATION; MATRILYSIN; PROGNOSIS; 3111 Biomedicine; 3122 Cancers N1 - PP - ER -