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T1  - Mass spectrometry-based proteomic exploration of the human immune system : focus on the inflammasome, global protein secretion, and T cells 
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UR  - http://hdl.handle.net/10138/234525 
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A1  - Nyman, Tuula A.; Lorey, Martina B.; Cypryk, Wojciech; Matikainen, Sampsa 
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Y1  - 2017 
LA  - eng 
AB  - Introduction: The immune system is our defense system against microbial infections and tissue injury, and understanding how it works in detail is essential for developing drugs for different diseases. Mass spectrometry-based proteomics can provide in-depth information on the molecular mechanisms involved in immune responses.Areas covered: Summarized are the key immunology findings obtained with MS-based proteomics in the past five years, with a focus on inflammasome activation, global protein se... 
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KW  - Immune system; mass spectrometry; inflammasome; protein secretion; innate immunity; T cell; HUMAN PRIMARY MACROPHAGES; QUANTITATIVE PROTEOMICS; EXTRACELLULAR VESICLES; ANTIVIRAL IMMUNITY; NLRP3 INFLAMMASOME; PHOSPHOPROTEOME CHARACTERIZATION; PEPTIDE REPERTOIRES; SIGNALING PATHWAYS; ANALYSIS REVEALS; VIRUS-INFECTION; 3111 Biomedicine; 1182 Biochemistry, cell and molecular biology 
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