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T1  - Maternal Thyroid Disease and the Risk of Childhood Cancer in the Offspring 
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UR  - http://hdl.handle.net/10138/338039 
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A1  - Seppälä, Laura K.; Madanat-Harjuoja, Laura-Maria; Leinonen, Maarit K.; Lääperi, Mitja; Vettenranta, Kim 
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Y1  - 2021 
LA  - eng 
AB  - Simple Summary:& nbsp;Maternal thyroid disease, especially hypothyroidism, is known to affect pregnancy and its outcome. We evaluated the risk of childhood cancer in the offspring following exposure to maternal thyroid disease in a case-control setting using registry data. In our study, maternal hypothyroidism was associated with an increased risk of lymphoma in the offspring. The association remained stable when possible familial cancers were excluded.Maternal thyroid disease, especially hypoth... 
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KW  - maternal thyroid disease; thyroid hormone; childhood cancer; adolescent cancer; cancer risk; case-control; registry-based; ACUTE LYMPHOBLASTIC-LEUKEMIA; AUTOIMMUNE-DISEASE; HODGKIN-LYMPHOMA; FAMILY-HISTORY; MEDICATION USE; BIRTH-WEIGHT; DATA QUALITY; CHILDREN; PREGNANCY; PREDISPOSITION; 3122 Cancers 
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