TY  -  
T1  - Maternal gut and breast milk microbiota affect infant gut antibiotic resistome and mobile genetic elements 
SN  -  /  
UR  - http://hdl.handle.net/10138/250564 
T3  -  
A1  - Pärnänen, Katariina; Karkman, Antti; Hultman, Jenni; Lyra, Christina; Bengtsson-Palme, Johan; Larsson, D. G. Joakim; Rautava, Samuli; Isolauri, Erika; Salminen, Seppo; Kumar, Himanshu; Satokari, Reetta; Virta, Marko 
A2  -  
PB  -  
Y1  - 2018 
LA  - eng 
AB  - The infant gut microbiota has a high abundance of antibiotic resistance genes (ARGs) compared to adults, even in the absence of antibiotic exposure. Here we study potential sources of infant gut ARGs by performing metagenomic sequencing of breast milk, as well as infant and maternal gut microbiomes. We find that fecal ARG and mobile genetic element (MGE) profiles of infants are more similar to those of their own mothers than to those of unrelated mothers. MGEs in mothers' breast milk are also sh... 
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KW  - RESISTANCE GENES; NECROTIZING ENTEROCOLITIS; PRETERM INFANTS; READ ALIGNMENT; RIBOSOMAL-RNA; 1ST YEAR; IDENTIFICATION; ASSOCIATION; DIVERSITY; WORLDWIDE; 11832 Microbiology and virology; 1184 Genetics, developmental biology, physiology 
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