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T1  - Matrix Metalloproteinase 8 Expression in a Tumour Predicts a Favourable Prognosis in Pancreatic Ductal Adenocarcinoma 
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UR  - http://hdl.handle.net/10138/342917 
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A1  - Kaasinen, Mirjami; Hagström, Jaana; Mustonen, Harri; Sorsa, Timo; Sund, Malin; Haglund, Caj; Seppänen, Hanna 
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Y1  - 2022 
LA  - eng 
AB  - Pancreatic ductal adenocarcinoma (PDAC) is a significant cause of cancer-related death globally, and, despite improvements in diagnostics and treatment, survival remains poor. Matrix metalloproteinases (MMPs) are enzymes involved in stroma remodelling in inflammation and cancer. MMP-8 plays a varied prognostic role in cancers of the gastrointestinal tract. We examined the prognostic value of MMP-8 immunoexpression in tumour tissue and the amount of MMP-8-positive polymorphonuclear cells (PMNs) i... 
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KW  - pancreatic cancer; matrix metalloproteinase 8; polymorphonuclear cell; C-reactive protein; COLLAGENASE-2 MMP-8; LYMPHOCYTE RATIO; CANCER; NEUTROPHILS; SURVIVAL; PROGRESSION; METASTASIS; DIAGNOSIS; 1182 Biochemistry, cell and molecular biology 
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