TY  -  
T1  - Matrix Metalloproteinases-8 and-9 and Tissue Inhibitor of Metalloproteinase-1 in Burn Patients. A Prospective Observational Study 
SN  -  /  
UR  - http://hdl.handle.net/10138/157015 
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A1  - Hästbacka, Johanna; Freden, Filip; Hult, Maarit; Bergquist, Maria; Wilkman, Erika; Vuola, Jyrki; Sorsa, Timo; Tervahartiala, Taina; Huss, Fredrik 
A2  -  
PB  -  
Y1  - 2015 
LA  - eng 
AB  - Introduction Matrix metalloproteinases (MMPs) -8 and -9 are released from neutrophils in acute inflammation and may contribute to permeability changes in burn injury. In retrospective studies on sepsis, levels of MMP-8, MMP-9, and tissue inhibitor of metalloproteinase-1 (TIMP-1) differed from those of healthy controls, and TIMP-1 showed an association with outcome. Our objective was to investigate the relationship between these proteins and disease severity and outcome in burn patients. Methods ... 
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KW  - CRITICALLY-ILL PATIENTS; SEVERE SEPSIS; GELATINASE B; EXPRESSION; TIMP-1; COLLAGENASE; INJURY; CELLS; SERUM; MATRIX-METALLOPROTEINASE-9; 3126 Surgery, anesthesiology, intensive care, radiology; 313 Dentistry 
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