TY - T1 - Matrix metalloproteinase-2,-7, and-9 activities in dogs with idiopathic pulmonary fibrosis compared to healthy dogs and dogs with other respiratory diseases SN - / UR - http://hdl.handle.net/10138/331343 T3 - A1 - Määttä, Merita; Laurila, Henna P.; Holopainen, Saila; Aaltonen, Kaisa; Lilja-Maula, Liisa; Viitanen, Sanna; Rajamaki, Minna M. A2 - PB - Y1 - 2021 LA - eng AB - Background Canine idiopathic pulmonary fibrosis (CIPF) is a chronic, interstitial lung disease that mainly affects West Highland white terriers (WHWTs) and is characterized by excessive deposition of extracellular matrix (ECM) in the lung. Matrix metalloproteinases (MMPs) participate in remodeling of ECM. Objectives To compare metalloproteinase-2, -7 and -9 activities in blood or bronchoalveolar lavage fluid (BALF) samples or both of CIPF WHWTs with healthy WHWTs, healthy dogs of other breeds, a... VO - IS - SP - OP - KW - canine; gelatinases; lung; matrilysin; HIGHLAND WHITE TERRIERS; GENE-EXPRESSION; MMP-7; BETA; MATRIX-METALLOPROTEINASE-9; PATHOGENESIS; MATRILYSIN; PROGNOSIS; MORTALITY; APOPTOSIS; 413 Veterinary science N1 - PP - ER -