TY - T1 - Membrane-assisted viral DNA ejection SN - / UR - http://hdl.handle.net/10138/233142 T3 - A1 - Santos-Perez, Isaac; Oksanen, Hanna M.; Bamford, Dennis H.; Goni, Felix M.; Reguera, David; Abrescia, Nicola G. A. A2 - PB - Y1 - 2017 LA - eng AB - Genome packaging and delivery are fundamental steps in the replication cycle of all viruses. Icosahedral viruses with linear double-stranded DNA (dsDNA) usually pacicage their genome into a preformed, rigid procapsid using the power generated by a virus-encoded packaging ATPase. The pressure and stored energy due to this confinement of DNA at a high density is assumed to drive the initial stages of genome ejection. Membrane-containing icosahedral viruses, such as bacteriophage PRD1, present an a... VO - IS - SP - OP - KW - Models of viral DNA packaging; Viral DNA delivery; Lipid-containing viruses; Membrane vesicle and properties; Biophysical modeling; Cryo-electron tomography; BACTERIOPHAGE PRD1; TURGOR PRESSURE; ELASTIC PROPERTIES; LIPID-BILAYERS; FORCES; PHAGE; VIRUSES; CAPSIDS; IMAGE; VISUALIZATION; 1183 Plant biology, microbiology, virology; 1182 Biochemistry, cell and molecular biology N1 - PP - ER -