TY - T1 - Men and women respond differently to rapid weight loss : Metabolic outcomes of a multi-centre intervention study after a low-energy diet in 2500 overweight, individuals with pre-diabetes (PREVIEW) SN - / UR - http://hdl.handle.net/10138/265094 T3 - A1 - Christensen, Pia; Larsen, Thomas Meinert; Westerterp-Plantenga, Margriet; Macdonald, Ian; Martinez, J. Alfredo; Handjiev, Svetoslav; Poppitt, Sally; Hansen, Sylvia; Ritz, Christian; Astrup, Arne; Pastor-Sanz, Laura; Sando-Pedersen, Finn; Pietiläinen, Kirsi H.; Sundvall, Jouko; Drummen, Mathijs; Taylor, Moira A.; Navas-Carretero, Santiago; Handjieva-Darlenska, Teodora; Brodie, Shannon; Silvestre, Marta P.; Huttunen-Lenz, Maija; Brand-Miller, Jennie; Fogelholm, Mikael; Raben, Anne A2 - PB - Y1 - 2018 LA - eng AB - Aims Materials and methods The PREVIEW lifestyle intervention study ( Identifier: NCT01777893) is, to date, the largest, multinational study concerning prevention of type-2 diabetes. We hypothesized that the initial, fixed low-energy diet (LED) would induce different metabolic outcomes in men vs women. All participants followed a LED (3.4 MJ/810 kcal/daily) for 8 weeks (Cambridge Weight Plan). Participants were recruited from 8 sites in Europe, Australia and New Zealand. Those eligible for inclu... VO - IS - SP - OP - KW - dietary intervention; obesity; prevention; weight loss; pre-diabetes; LOW-CALORIE DIET; GENDER-DIFFERENCES; BARIATRIC SURGERY; PHYSICAL-ACTIVITY; BODY-COMPOSITION; FAT; MAINTENANCE; MANAGEMENT; REDUCTION; EXERCISE; 3121 General medicine, internal medicine and other clinical medicine N1 - PP - ER -