TY  -  
T1  - Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Upregulated with Therapeutic Fasting in Humans and Diet Fat Withdrawal in Obese Mice 
SN  -  /  
UR  - http://hdl.handle.net/10138/306803 
T3  -  
A1  - Galli, Emilia; Rossi, Jari; Neumann, Thomas; Andressoo, Jaan-Olle; Drinda, Stefan; Lindholm, Päivi 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - Dietary restriction induces beneficial metabolic changes and prevents age-related deterioration. Mesencephalic astrocyte-derived neurotrophic factor (MANF) shows protective effects on cells in various models of degenerative diseases. Here we studied whether circulating concentrations of MANF are associated with fasting-induced positive effects. We quantified the levels of circulating MANF from 40 human subjects before and after therapeutic fasting. As measured by an enzyme-linked immunosorbent a... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - ENDOPLASMIC-RETICULUM STRESS; UNFOLDED PROTEIN RESPONSE; ISCHEMIA; MANF; PROLIFERATION; ADIPONECTIN; HOMEOSTASIS; EXPRESSION; BINDING; LEPTIN; 3111 Biomedicine 
N1  -   
PP  -  
ER  -