TY  -  
T1  - Meta-Analysis of Placental Transcriptome Data Identifies a Novel Molecular Pathway Related to Preeclampsia 
SN  -  /  
UR  - http://hdl.handle.net/10138/160418 
T3  -  
A1  - van Uitert, Miranda; Moerland, Perry D.; Enquobahrie, Daniel A.; Laivuori, Hannele; van der Post, Joris A. M.; Ris-Stalpers, Carrie; Afink, Gijs B. 
A2  -  
PB  -  
Y1  - 2015 
LA  - eng 
AB  - Studies using the placental transcriptome to identify key molecules relevant for preeclampsia are hampered by a relatively small sample size. In addition, they use a variety of bioinformatics and statistical methods, making comparison of findings challenging. To generate a more robust preeclampsia gene expression signature, we performed a meta-analysis on the original data of 11 placenta RNA microarray experiments, representing 139 normotensive and 116 preeclamptic pregnancies. Microarray data w... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - RUBINSTEIN-TAYBI-SYNDROME; GENE-EXPRESSION; MICROARRAY ANALYSIS; PREGNANCIES; HYPOXIA; GROWTH; EP300; UPDATE; PATHOGENESIS; RECRUITMENT; 3111 Biomedicine 
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ER  -