TY - T1 - Metabolomic signature of amino acids in plasma of patients with non-segmental Vitiligo SN - / UR - http://hdl.handle.net/10138/335165 T3 - A1 - Marzabani, Rezvan; Rezadoost, Hassan; Choopanian, Peyman; Kolahdooz, Sima; Mozafari, Nikoo; Mirzaie, Mehdi; Karimi, Mehrdad; Nieminen, Anni; Jafari, Mohieddin A2 - PB - Y1 - 2021 LA - eng AB - Introduction Vitiligo pathogenesis is complicated, and several possibilities were suggested. However, it is well-known that the metabolism of pigments plays a significant role in the pathogenicity of the disease. Objectives We explored the role of amino acids in vitiligo using targeted metabolomics. Methods The amino acid profile was studied in plasma using liquid chromatography. First, 22 amino acids were derivatized and precisely determined. Next, the concentrations of the amino acids and the ... VO - IS - SP - OP - KW - Vitiligo; Plasma; Metabolomics; Amino acids; Liquid chromatography; UROCANIC ACID; GLUTAMATE; PHOTORECEPTOR; HOMOCYSTEINE; BIOMARKERS; ARGINASE; GENETICS; PROLINE; ANXIETY; SKIN; 3121 General medicine, internal medicine and other clinical medicine N1 - PP - ER -