TY  -  
T1  - MicroRNA-192*impairs adipocyte triglyceride storage 
SN  -  /  
UR  - http://hdl.handle.net/10138/223915 
T3  -  
A1  - Mysore, Raghavendra; Zhou, You; Sädevirta, Sanja; Savolainen-Peltonen, Hanna; Haridas, P. A. Nidhina; Soronen, Jarkko; Leivonen , Marja; Sarin, Antti-Pekka; Fischer-Posovszky, Pamela; Wabitsch, Martin; Yki-Jarvinen, Hannele; Olkkonen, Vesa M. 
A2  -  
PB  -  
Y1  - 2016 
LA  - eng 
AB  - We investigated the expression of miR-192* (miR-192-3p) in the visceral adipose tissue (VAT) of obese subjects and its function in cultured human adipocytes. This miRNA is a 3' arm derived from the same pre-miRNA as miR-192 (miR-192-5p) implicated in type 2 diabetes, liver disease and cancers, and is predicted to target key genes in lipid metabolism. In morbidly obese subjects undergoing bariatric surgery preceded by a very low calorie diet, miR-192* in VAT correlated negatively (r = -0.387; p =... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - Adipogenesis; miR-192-3p; Obesity; SGBS; Transcriptome; STEAROYL-COA DESATURASE-1; CARDIOVASCULAR-DISEASE; ADIPOSE-TISSUE; GENE-EXPRESSION; PROTECTS MICE; LIVER-DISEASE; DIFFERENTIATION; MICRORNAS; OBESITY; RISK; 3111 Biomedicine 
N1  -   
PP  -  
ER  -