TY - T1 - Mining microbial metatranscriptomes for expression of antibiotic resistance genes under natural conditions SN - / UR - http://hdl.handle.net/10138/162448 T3 - A1 - Versluis, Dennis; D'Andrea, Marco Maria; Garcia, Javier Ramiro; Leimena, Milkha M.; Hugenholtz, Floor; Zhang, Jing; Ozturk, Basak; Nylund, Lotta; Sipkema, Detmer; van Schaik, Willem; de Vos, Willem M.; Kleerebezem, Michiel; Smidt, Hauke; van Passel, Mark W. J. A2 - PB - Y1 - 2015 LA - eng AB - Antibiotic resistance genes are found in a broad range of ecological niches associated with complex microbiota. Here we investigated if resistance genes are not only present, but also transcribed under natural conditions. Furthermore, we examined the potential for antibiotic production by assessing the expression of associated secondary metabolite biosynthesis gene clusters. Metatranscriptome datasets from intestinal microbiota of four human adults, one human infant, 15 mice and six pigs, of whi... VO - IS - SP - OP - KW - ESCHERICHIA-COLI; BACTERIAL; SOIL; DIVERSITY; SEQUENCES; RESERVOIR; IDENTIFICATION; ENVIRONMENTS; PATHWAYS; PIGS; 3111 Biomedicine N1 - PP - ER -