TY - T1 - Mitochondrial bioenergetic pathways in blood leukocyte transcriptome decrease after intensive weight loss but are rescued following weight regain in female physique athletes SN - / UR - http://hdl.handle.net/10138/330827 T3 - A1 - Sarin, Heikki V.; Pirinen, Eija; Pietiläinen, Kirsi H.; Isola, Ville; Häkkinen, Keijo; Perola, Markus; Hulmi, Juha J. A2 - PB - Y1 - 2021 LA - eng AB - Prolonged periods of energy deficit leading to weight loss induce metabolic adaptations resulting in reduced energy expenditure, but the mechanisms for energy conservation are incompletely understood. We examined 42 healthy athletic females (age 27.5 +/- 4.0 years, body mass index 23.4 +/- 1.7 kg/m(2)) who volunteered into either a group dieting for physique competition (n = 25) or a control group (n = 17). The diet group substantially reduced their energy intake and moderately increased exercis... VO - IS - SP - OP - KW - diet; exercise; leukocytes; oxidative phosphorylation; ribosomes; 3111 Biomedicine; 1182 Biochemistry, cell and molecular biology N1 - PP - ER -