TY - T1 - Modifiable pathways for colorectal cancer : a mendelian randomisation analysis SN - / UR - http://hdl.handle.net/10138/309630 T3 - A1 - Cornish, Alex J.; Law, Philip J.; Timofeeva, Maria; Palin, Kimmo; Farrington, Susan M.; Palles, Claire; Jenkins, Mark A.; Casey, Graham; Brenner, Hermann; Chang-Claude, Jenny; Hoffmeister, Michael; Kirac, Iva; Maughan, Tim; Brezina, Stefanie; Gsur, Andrea; Cheadle, Jeremy P.; Aaltonen, Lauri A.; Tomlinson, Ian; Dunlop, Malcolm G.; Houlston, Richard S. A2 - PB - Y1 - 2020 LA - eng AB - Background Epidemiological studies have linked lifestyle, cardiometabolic, reproductive, developmental, and inflammatory factors to the risk of colorectal cancer. However, which specific factors affect risk and the strength of these effects are unknown. We aimed to examine the relationship between potentially modifiable risk factors and colorectal cancer. Methods We used a random-effects model to examine the relationship between 39 potentially modifiable risk factors and colorectal cancer in 26 ... VO - IS - SP - OP - KW - INSTRUMENTS; ASSOCIATION; BIAS; 3121 General medicine, internal medicine and other clinical medicine; 3122 Cancers N1 - PP - ER -