TY - T1 - Modifying the minimum criteria for diagnosing amnestic MCI to improve prediction of brain atrophy and progression to Alzheimer’s disease SN - / UR - http://hdl.handle.net/10138/316690 T3 - A1 - Vuoksimaa, Eero; McEvoy, Linda K.; Holland, Dominic; Franz, Carol E.; Kremen, William S. A2 - PB - Y1 - 2020 LA - eng AB - Mild cognitive impairment (MCI) is a heterogeneous condition with variable outcomes. Improving diagnosis to increase the likelihood that MCI reliably reflects prodromal Alzheimer's Disease (AD) would be of great benefit for clinical practice and intervention trials. In 230 cognitively normal (CN) and 394 MCI individuals from the Alzheimer's Disease Neuroimaging Initiative, we studied whether an MCI diagnostic requirement of impairment on at least two episodic memory tests improves 3-year predict... VO - IS - SP - OP - KW - 3112 Neurosciences; 3124 Neurology and psychiatry; Alzheimer's disease; Biomarkers; Early detection; Mild cognitive impairment; Neuropsychological testing; MILD COGNITIVE IMPAIRMENT; SURFACE-BASED ANALYSIS; VERBAL-LEARNING TEST; ASSOCIATION WORKGROUPS; HYPOTHETICAL MODEL; NATIONAL INSTITUTE; MARKERS; RECOMMENDATIONS; SEGMENTATION; BIOMARKERS N1 - PP - ER -