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T1  - Modulation of microglial phagocytosis in vitro 
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UR  - URN:NBN:fi:hulib-202108253497; http://hdl.handle.net/10138/333541 
T3  -  
A1  - Järvinen, Elli Katariina 
A2  -  
PB  - Helsingin yliopisto 
Y1  - 2021 
LA  - eng 
AB  - Ischemic stroke is a complex disease involving multiple pathophysiological mechanisms. To date, many therapeutic intervention strategies such as anti-inflammatory treatments have been tested, but none of them has been successful. Previous studies have shown that mesencephalic astrocyte-derived neurotrophic factor (MANF) improves stroke recovery and increases the expression of phagocytosis related genes. In this study, the phagocytic and inflammatory effect of monocyte chemoattractant protein 1 (... 
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KW  - ischemic stroke; microglia; phagocytosis; ER stress; ADGRE1; C3; C3a; MANF; MCP-1; M-CSF; MerTK; Neuroscience and psychobiology; Neuroscience and psychobiology; Neuroscience and psychobiology; Translationaalisen lääketieteen maisteriohjelma (Translational Medicine); Master's Programme in Translational Medicine; Magisterprogrammet i translationell medicin 
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