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T1  - Molecular Fingerprint and Developmental Regulation of the Tegmental GABAergic and Glutamatergic Neurons Derived from the Anterior Hindbrain 
SN  -  /  
UR  - http://hdl.handle.net/10138/321128 
T3  -  
A1  - Morello, Francesca; Borshagovski, Daniel; Survila, Mantas; Tikker, Laura; Sadik-Ogli, Samir; Kirjavainen, Anna; Estartús, Nuri; Knaapi, Laura; Lahti, Laura; Törönen, Petri; Mazutis, Linas; Delogu, Alessio; Salminen, Marjo; Achim, Kaia; Partanen, Juha 
A2  -  
PB  -  
Y1  - 2020 
LA  - eng 
AB  - Tegmental nuclei in the ventral midbrain and anterior hindbrain control motivated behavior, mood, memory, and movement. These nuclei contain inhibitory GABAergic and excitatory glutamatergic neurons, whose molecular diversity and development remain largely unraveled. Many tegmental neurons originate in the embryonic ventral rhombomere 1 (r1), where GABAergic fate is regulated by the transcription factor (TF) Tal1. We used single-cell mRNA sequencing of the mouse ventral r1 to characterize the Ta... 
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KW  - TRANSCRIPTION FACTOR; EXCITATORY NEURONS; CELL; EXPRESSION; NOTCH; PROGENITOR; DIFFERENTIATION; FAMILY; GENES; FATE; 1182 Biochemistry, cell and molecular biology; 1184 Genetics, developmental biology, physiology 
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ER  -