TY  -  
T1  - Molecular alterations in pediatric brainstem gliomas 
SN  -  /  
UR  - http://hdl.handle.net/10138/302389 
T3  -  
A1  - Porkholm, Mikaela; Raunio, Anna; Vainionpää, Reetta; Salonen, Tarja; Hernesniemi, Juha; Valanne, Leena; Satopää, Jarno; Karppinen, Atte; Oinas, Minna; Tynninen, Olli; Kivivuori, Sanna-Maria 
A2  -  
PB  -  
Y1  - 2018 
LA  - eng 
AB  - BackgroundDiffuse intrinsic pontine gliomas (DIPGs) have a dismal prognosis. Previously, diagnosis was based on a typical clinical presentation and magnetic resonance imaging findings. After the start of the era of biopsies, DIPGs bearing H3 K27 mutations have been reclassified into a novel entity, diffuse midline glioma, based on the presence of this molecular alteration. However, it is not well established how clinically diagnosed DIPG overlap with H3 K27-mutated diffuse midline gliomas, and w... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - 3122 Cancers; 3123 Gynaecology and paediatrics 
N1  -   
PP  -  
ER  -