TY  -  
T1  - Molecular background of double protein expressor B-cell lymphoma 
SN  -  /  
UR  - URN:NBN:fi:hulib-201912124137; http://hdl.handle.net/10138/308269 
T3  -  
A1  - Meriranta, Leo 
A2  -  
PB  - Helsingin yliopisto 
Y1  - 2019 
LA  - eng 
AB  - Concomitant deregulation of MYC and BCL2, whether at the genomic or protein level, comprises a clinically significant poorly characterized biological high-risk feature in diffuse large B-cell lymphoma (DLBCL). To interrogate these lymphomas, we comprehensively characterized genomic alterations and protein expression of BCL2, BCL6 and MYC in the context of comprehensive mutational, transcriptomic and clinical data in 181 patients with primary DLBCL. While the structural variations of BCL2 were su... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - Diffuse large B-cell lymphoma; Double protein expression; MYC; BCL2; TP53 
N1  -   
PP  -  
ER  -