TY  -  
T1  - Multifunctional Nanohybrid Based on Porous Silicon Nanoparticles, Gold Nanoparticles and Acetalated Dextran for Liver Regeneration and Acute Liver Failure Theranostics 
SN  -  /  
UR  - http://hdl.handle.net/10138/327342 
T3  -  
A1  - Liu, Zehua; Li, Yunzhan; Li, Wei; Xiao, Chen; Liu, Dongfei; Dong, Chao; Zhang, Ming; Mäkilä, Ermei; Kemell, Marianna; Salonen, Jarno; Hirvonen, Jouni T.; Zhang, Hongbo; Zhou, Dawang; Deng, Xianming; Santos, Helder A. 
A2  -  
PB  -  
Y1  - 2018 
LA  - eng 
AB  - Herein, a novel nanohybrid based on porous silicon, gold nanoparticles (Au NPs), and acetalated dextran (DPSi/DAu@AcDEX) is reported to encapsulate and deliver one drug and increase the computer tomography (CT) signal for acute-liver-failure (ALF) theranostics. A microfluidic-assisted method is used to co-encapsulate different NPs in a single step. By alternating the surface properties of different NPs and by modulating the composition of the organic phase, both PSi and Au NPs are effectively en... 
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KW  - 317 Pharmacy; liver regeneration; nanohybrids; nanoparticles; porous silicon; theranostic; IN-VITRO; COMPUTED-TOMOGRAPHY; IMAGING APPEARANCE; CANCER-THERAPY; DELIVERY; INFLAMMATION; NANOCOMPOSITES; RECRUITMENT; DIAGNOSIS; FIBROSIS; 116 Chemical sciences; 221 Nano-technology; 216 Materials engineering 
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