TY - T1 - Multiple formin proteins participate in glioblastoma migration SN - / UR - http://hdl.handle.net/10138/319345 T3 - A1 - Heuser, Vanina D.; Kiviniemi, Aida; Lehtinen, Laura; Munthe, Sune; Kristensen, Bjarne Winther; Posti, Jussi P.; Sipilä, Jussi O. T.; Vuorinen, Ville; Carpen, Olli; Gardberg, Maria A2 - PB - Y1 - 2020 LA - eng AB - BackgroundThe prognosis of glioblastoma remains poor, related to its diffuse spread within the brain. There is an ongoing search for molecular regulators of this particularly invasive behavior. One approach is to look for actin regulating proteins that might be targeted by future anti-cancer therapy. The formin family of proteins orchestrates rearrangement of the actin cytoskeleton in multiple cellular processes. Recently, the formin proteins mDia1 and mDia2 were shown to be expressed in gliobla... VO - IS - SP - OP - KW - Actin; Formin; Glioma; Glioblastoma; Migration; Spheroid; FHOD1; INF2; Knockdown; Immunohistochemistry; Outcome; GLIOMA-CELL MIGRATION; TUMORS; 3122 Cancers N1 - PP - ER -