TY - T1 - Multiplexed High-Throughput Serological Assay for Human Enteroviruses SN - / UR - http://hdl.handle.net/10138/318452 T3 - A1 - Saarinen, Niila V. V.; Lehtonen, Jussi; Veijola, Riitta; Lempainen, Johanna; Knip, Mikael; Hyöty, Heikki; Laitinen, Olli H.; Hytönen, Vesa P. A2 - PB - Y1 - 2020 LA - eng AB - Immunological assays detecting antibodies against enteroviruses typically use a single enterovirus serotype as antigen. This limits the ability of such assays to detect antibodies against different enterovirus types and to detect possible type-specific variation in antibody responses. We set out to develop a multiplexed assay for simultaneous detection of antibodies against multiple enterovirus and rhinovirus types encompassing all human infecting species. Seven recombinant VP1 proteins from ent... VO - IS - SP - OP - KW - enterovirus; rhinovirus; multiplex immunoassay; INCREASED RISK; RHINOVIRUS; VIRUS; MYOCARDITIS; ANTIBODIES; INFECTION; CHILDREN; VP1; 11832 Microbiology and virology N1 - PP - ER -