TY  -  
T1  - Myosin-18B Promotes the Assembly of Myosin II Stacks for Maturation of Contractile Actomyosin Bundles 
SN  -  /  
UR  - http://hdl.handle.net/10138/288205 
T3  -  
A1  - Jiu, Yaming; Kumari, Reena; Fenix, Aidan M.; Schaible, Niccole; Liu, Xiaonan; Varjosalo, Markku; Krishnan, Ramaswamy; Burnette, Dylan T.; Lappalainen, Pekka 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - Summary Cell adhesion, morphogenesis, mechanosensing, and muscle contraction rely on contractile actomyosin bundles, where the force is produced through sliding of bipolar myosin II filaments along actin filaments. The assembly of contractile actomyosin bundles involves registered alignment of myosin II filaments and their subsequent fusion into large stacks. However, mechanisms underlying the assembly of myosin II stacks and their physiological functions have remained elusive. Here, we identifi... 
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IS  -  
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KW  - myosin-18B; actin; stress fiber; actomyosin bundles; myosin II; cytoskeleton; mechanosensing; cell migration; 1182 Biochemistry, cell and molecular biology 
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ER  -