TY - T1 - Narcolepsy Associated with Pandemrix Vaccine SN - / UR - http://hdl.handle.net/10138/302445 T3 - A1 - Sarkanen, Tomi; Alakuijala, Anniina; Julkunen, Ilkka; Partinen, Markku A2 - PB - Y1 - 2018 LA - eng AB - After the connection between AS03-adjuvanted pandemic H1N1 vaccine Pandemrix and narcolepsy was recognized in 2010, research on narcolepsy has been more intensive than ever before. The purpose of this review is to provide the reader with current concepts and recent findings on the Pandemrix-associated narcolepsy. After the Pandemrix vaccination campaign in 2009-2010, the risk of narcolepsy was increased 5- to 14-fold in children and adolescents and 2- to 7-fold in adults. According to observatio... VO - IS - SP - OP - KW - Narcolepsy; H1N1 vaccination; Vaccines; Pandemrix; Hypocretin; Orexin; 2009 INFLUENZA VACCINE; TRIB2 AUTOANTIBODIES; H1N1 VACCINATION; CONFER RISK; CATAPLEXY; ANTIBODIES; ONSET; CHILDREN; ANTIGANGLIOSIDE; PROTECTION; 3112 Neurosciences; 3124 Neurology and psychiatry N1 - PP - ER -