TY - T1 - Natural Course of Frailty Components in People Who Develop Frailty Syndrome : Evidence From Two Cohort Studies SN - / UR - http://hdl.handle.net/10138/306011 T3 - A1 - Stenholm, Sari; Ferrucci, Luigi; Vahtera, Jussi; Hoogendijk, Emiel O.; Huisman, Martijn; Pentti, Jaana; Lindbohm, Joni V.; Bandinelli, Stefania; Guralnik, Jack M.; Kivimäki, Mika A2 - PB - Y1 - 2019 LA - eng AB - Background: Frailty is an important geriatric syndrome, but little is known about its development in the years preceding onset of the syndrome. The aim of this study was to examine the progression of frailty and compare the trajectories of each frailty component prior to frailty onset. Methods: Repeat data were from two cohort studies: the Longitudinal Aging Study Amsterdam (n = 1440) with a 15-year follow-up and the InCHIANTI Study (n = 998) with a 9-year follow-up. Participants were classified... VO - IS - SP - OP - KW - Frailty; Exhaustion; Walking speed; Physical activity; Muscle strength; POISSON REGRESSION APPROACH; OLDER-ADULTS; WOMENS HEALTH; FATIGUE; DISABILITY; TRANSITIONS; MORTALITY; PREDICTION; FRACTURES; PHENOTYPE; 3121 General medicine, internal medicine and other clinical medicine N1 - PP - ER -