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T1  - Neuroticism Associates with Cerebral in Vivo Serotonin Transporter Binding Differently in Males and Females 
SN  -  /  
UR  - http://hdl.handle.net/10138/232897 
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A1  - Tuominen, Lauri; Miettunen, Jouko; Cannon, Dara M.; Drevets, Wayne C.; Frokjaer, Vibe G.; Hirvonen, Jussi; Ichise, Masanori; Jensen, Peter S.; Keltikangas-Järvinen, Liisa; Klaver, Jacqueline M.; Knudsen, Gitte M.; Takano, Akihiro; Suhara, Tetsuya; Hietala, Jarmo 
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Y1  - 2017 
LA  - eng 
AB  - Background: Neuroticism is a major risk factor for affective disorders. This personality trait has been hypothesized to associate with synaptic availability of the serotonin transporter, which critically controls serotonergic tone in the brain. However, earlier studies linking neuroticism and serotonin transporter have failed to produce converging findings. Because sex affects both the serotonergic system and the risk that neuroticism poses to the individual, sex may modify the association betwe... 
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KW  - neuroticism; sex; serotonin; serotonin transporter; PET; POSITRON-EMISSION-TOMOGRAPHY; MAJOR DEPRESSIVE DISORDER; TEST-RETEST REPRODUCIBILITY; POPULATION-BASED TWIN; 2A RECEPTOR-BINDING; BODY-MASS INDEX; HUMAN BRAIN; GENDER-DIFFERENCES; HEALTHY-SUBJECTS; POSTMENOPAUSAL WOMEN; 515 Psychology; 3112 Neurosciences; 3141 Health care science 
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