TY - T1 - Neurotrophin receptor Ntrk2b function in the maintenance of dopamine and serotonin neurons in zebrafish SN - / UR - http://hdl.handle.net/10138/300208 T3 - A1 - Sahu, Madhusmita Priyadarshini; Pazos-Boubeta, Yago; Pajanoja, Ceren; Rozov, Stanislav; Panula, Pertti; Castren, Eero A2 - PB - Y1 - 2019 LA - eng AB - Neurotrophins and their receptors have highly conserved evolutionary lineage in vertebrates including zebrafish. The NTRK2 receptor has two isoforms in zebrafish, Ntrk2a and Ntrk2b. The spatio-temporal expression pattern of bdnf and ntrk2b in the zebrafish brain was studied using in situ hybridization. The robust and corresponding expression pattern of ntrk2b to bdnf suggests that ntrk2b is the key receptor for bdnf in the zebrafish brain, unlike its duplicate isoform ntrk2a. To study ntrk2b fun... VO - IS - SP - OP - KW - ADULT ZEBRAFISH; BRAIN; BDNF; TRKB; EXPRESSION; SYSTEM; ACTIVATION; LOCALIZATION; PLASTICITY; PHENOTYPE; 3112 Neurosciences; 3111 Biomedicine N1 - PP - ER -