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T1  - Normal extinction and reinstatement of morphine-induced conditioned place preference in the GluA1-KO mouse line 
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UR  - http://hdl.handle.net/10138/323398 
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A1  - Kiiskinen, Tuomo; Korpi, Esa R.; Aitta-aho, Teemu 
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Y1  - 2019 
LA  - eng 
AB  - Extinction and reinstatement of morphine-induced conditioned place preference were studied in glutamate α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-receptor GluA1 subunit-deficient mice (global GluA1-KO mice). In line with previous findings, both acquisition and expression of conditioned place preference to morphine (20 mg/kg, subcutaneously) were fully functional in GluA1 KO mice compared with wild-type littermate controls (GluA1-WT), thus enabling the study of extinction. With a 10-se... 
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KW  - 317 Pharmacy; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; conditioned place preference; extinction; glutamate; morphine; rat; reinstatement; COCAINE-INDUCED REINSTATEMENT; NUCLEUS-ACCUMBENS CORE; LONG-TERM POTENTIATION; AMPA RECEPTORS; SYNAPTIC PLASTICITY; GLUTAMATE RECEPTORS; DOPAMINE NEURONS; GLUR1 SUBUNIT; RELAPSE; SEEKING 
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