TY - T1 - Normal extinction and reinstatement of morphine-induced conditioned place preference in the GluA1-KO mouse line SN - / UR - http://hdl.handle.net/10138/323398 T3 - A1 - Kiiskinen, Tuomo; Korpi, Esa R.; Aitta-aho, Teemu A2 - PB - Y1 - 2019 LA - eng AB - Extinction and reinstatement of morphine-induced conditioned place preference were studied in glutamate α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-receptor GluA1 subunit-deficient mice (global GluA1-KO mice). In line with previous findings, both acquisition and expression of conditioned place preference to morphine (20 mg/kg, subcutaneously) were fully functional in GluA1 KO mice compared with wild-type littermate controls (GluA1-WT), thus enabling the study of extinction. With a 10-se... VO - IS - SP - OP - KW - 317 Pharmacy; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; conditioned place preference; extinction; glutamate; morphine; rat; reinstatement; COCAINE-INDUCED REINSTATEMENT; NUCLEUS-ACCUMBENS CORE; LONG-TERM POTENTIATION; AMPA RECEPTORS; SYNAPTIC PLASTICITY; GLUTAMATE RECEPTORS; DOPAMINE NEURONS; GLUR1 SUBUNIT; RELAPSE; SEEKING N1 - PP - ER -