TY  -  
T1  - Novel Aspects of Toxicity Mechanisms of Dioxins and Related Compounds 
SN  -  /  
UR  - http://hdl.handle.net/10138/324857 
T3  -  
A1  - Pohjanvirta, Raimo; Viluksela, Matti 
A2  -  
PB  -  
Y1  - 2020 
LA  - eng 
AB  - Dioxins and related compounds are common environmental contaminants. Although their levels have gone down, they are still of concern, in particular regarding developmental toxicity. The adverse effects of these compounds are mediated by the aryl hydrocarbon receptor (AHR), whose canonical signaling pathway has been unveiled in fair detail. The alternative (non-genomic) pathways are much more obscure. AHR has also proven to be a master regulator of numerous physiological phenomena, which has led ... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - 2; 3; 7; 8-Tetrachlorodibenzo-p-dioxin; TCDD; dioxins; halogenated aromatic hydrocarbons; polycyclic aromatic hydrocarbons; aryl hydrocarbon receptor; toxicity mechanisms; developmental toxicity; MONO-ADP-RIBOSYLTRANSFERASE; RECEPTOR; 2,3,7,8-TETRACHLORODIBENZO-PARA-DIOXIN; TIPARP; 1182 Biochemistry, cell and molecular biology 
N1  -   
PP  -  
ER  -