TY  -  
T1  - Novel ZNF414 activity characterized by integrative analysis of ChIP-exo, ATAC-seq and RNA-seq data 
SN  -  /  
UR  - http://hdl.handle.net/10138/343695 
T3  -  
A1  - Rodriguez-Martinez, Alejandra; Vuorinen, Elisa M.; Shcherban, Anastasia; Uusi-Mäkelä, Joonas; Rajala, Nina K. M.; Nykter, Matti; Kallioniemi, Anne 
A2  -  
PB  -  
Y1  - 2022 
LA  - eng 
AB  - Transcription factor binding to DNA is a central mechanism regulating gene expression. Thus, thorough characterization of this process is essential for understanding cellular biology in both health and disease. We combined data from three sequencing-based methods to unravel the DNA binding function of the novel ZNF414 protein in cells representing two tumor types. ChIP-exo served to map protein binding sites, ATAC-seq allowed identification of open chromatin, and RNA-seq examined the transcripto... 
VO  -  
IS  -  
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OP  -  
KW  - ZNF414; ChIP-exo; Transcription factor; Gene regulation; ATAC-seq; PROTEOME-SCALE MAP; DNA-BINDING; GLUCOCORTICOID-RECEPTOR; READ ALIGNMENT; PROTEINS; RECOGNITION; EVOLUTION; KPNA7; 1182 Biochemistry, cell and molecular biology 
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ER  -