TY  -  
T1  - Nuclear ubiquitin C-terminal hydrolase L5 expression associates with increased patient survival in pancreatic ductal adenocarcinoma 
SN  -  /  
UR  - http://hdl.handle.net/10138/222488 
T3  -  
A1  - Arpalahti, Leena; Saukkonen, Kapo; Hagström, Jaana; Mustonen, Harri; Seppänen, Hanna; Haglund, Caj; Holmberg, Carina I. 
A2  -  
PB  -  
Y1  - 2017 
LA  - eng 
AB  - Pancreatic ductal adenocarcinoma is a lethal disease with an overall 5-year survival of less than 5%. Prognosis among surgically treated patients is difficult and identification of new biomarkers is essential for accurate prediction of patient outcome. As part of one of the major cellular protein degradation systems, the proteasome plays a fundamental role in both physiological and pathophysiological conditions including cancer. The proteasome-associated deubiquitinating enzyme ubiquitin C-termi... 
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OP  -  
KW  - Deubiquitination; pancreatic ductal adenocarcinoma; prognosis; proteasome; ubiquitin C-terminal hydrolase L5; UCHL5; PROTEASOME INHIBITORS; MULTIPLE-MYELOMA; CELL-MIGRATION; CANCER; BORTEZOMIB; SYSTEM; UCH37; DEUBIQUITINASES; ACTIVATION; BIOMARKERS; 3122 Cancers 
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ER  -