TY  -  
T1  - On the Role of Histamine Receptors in the Regulation of Circadian Rhythms 
SN  -  /  
UR  - http://hdl.handle.net/10138/159765 
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A1  - Rozov, Stanislav V.; Porkka-Heiskanen, Tarja; Panula, Pertti 
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Y1  - 2015 
LA  - eng 
AB  - Several lines of evidence suggest a regulatory role of histamine in circadian rhythms, but little is known about signaling pathways that would be involved in such a putative role. The aim of this study was to examine whether histamine mediates its effects on the circadian system through Hrh1 or Hrh3 receptors. We assessed both diurnal and free-running locomotor activity rhythms of Hrh1(-/-) and Hrh3(-/-) mice. We also determined the expression of Per1, Per2 and Bmal1 genes in the suprachiasmatic... 
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KW  - RAT SUPRACHIASMATIC NUCLEUS; CLOCK GENE-EXPRESSION; LOCOMOTOR-ACTIVITY; BEHAVIORAL CHARACTERIZATION; HISTIDINE-DECARBOXYLASE; PORTACAVAL ANASTOMOSIS; H-3 RECEPTORS; PHASE-SHIFTS; BRAIN; NEURONS; 3112 Neurosciences; 3111 Biomedicine 
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