TY  -  
T1  - Oncolytic viruses for cancer immunotherapy 
SN  -  /  
UR  - http://hdl.handle.net/10138/318395 
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A1  - Hemminki, Otto; dos Santos, Joao Manuel; Hemminki, Akseli 
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PB  -  
Y1  - 2020 
LA  - eng 
AB  - In this review, we discuss the use of oncolytic viruses in cancer immunotherapy treatments in general, with a particular focus on adenoviruses. These serve as a model to elucidate how versatile viruses are, and how they can be used to complement other cancer therapies to gain optimal patient benefits. Historical reports from over a hundred years suggest treatment efficacy and safety with adenovirus and other oncolytic viruses. This is confirmed in more contemporary patient series and multiple cl... 
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KW  - Adenovirus; Oncolytic; Tumor; Cancer; Immunotherapy; Review; Immunology; Immune system; Immunosupression; ANTITUMOR IMMUNE-RESPONSES; COLONY-STIMULATING FACTOR; NECROSIS-FACTOR-ALPHA; PHASE-I TRIAL; OVARIAN-CANCER; GENE-TRANSFER; CELL THERAPY; GM-CSF; TALIMOGENE LAHERPAREPVEC; REPLICATION-COMPETENT; 3122 Cancers 
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